About this Book

This book is part of a series of books for the Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL) of the National Human Genome Research Institute (NHGRI). Learn more about AnVIL by visiting https://anvilproject.org or reading the article in Cell Genomics.

Skills Level

Genetics
Beginner: minimal genetics knowledge needed

Programming skills
Beginner: minimal programming experience needed

Learning Objectives

This activity addresses the following Core Concepts and Competencies as stated in the Genetics Core Competencies:

  1. Core Competency: Critique large data sets and use bioinformatics to assess genetics data.
  2. Core Competency: Generate and interpret graphs displaying experimental results.
  3. Evolution and Population Genetics: Explain how natural selection and genetic drift can affect the elimination, maintenance or increase in frequency of various types of alleles (e.g. dominant, recessive, deleterious, beneficial) in a population.

This activity also addresses the following core competency from the Bioinformatics core competencies for undergraduate life sciences education from [NIBLSE] (https://journals.plos.org/plosone/article/figure?id=10.1371/journal.pone.0196878.t002):

  1. Use bioinformatics tools to examine complex biological problems in evolution, information flow, and other important areas of biology.
  2. Use command-line bioinformatics tools and write simple computer scripts.

Course details

Course Audience

  • Undergraduate biology majors
  • Graduate students with less exposure to bioinformatics

Course Prerequisites

  • Layman understanding of genetics (understanding of DNA, genes, trait inheritance)
  • Some previous exposure to graphing

Class Type

  • Lab
  • Computer-based

Class Size

  • 1-50

Lesson Duration

Coming soon!

Assessment Type

  • Short answer questions at each lab stage

AnVIL Collection

Please check out our full collection of AnVIL and related resources: https://hutchdatascience.org/AnVIL_Collection/

All illustrations CC-BY.
All other materials CC-BY unless noted otherwise.