W2: Working with data structures

W1: Clearest Points / Positives

The responses to all the questions is fantastic. I really feel like I can ask anything which is so helpful!

Having someone in the chat helping those who are remote and the instructor is comforting

In general, coding is new to me (I work with data entry, so I do know the relevance), but I learned more details of how it a code is a language to the computer and will output information/answers.

Understanding how R/R Studio/Posit imports data, and runs from the console.

Be patient. It takes some time getting used to R coming from elsewhere.

Clearest Points

That in R you can use the equal sign to assign variables instead of the arrow

Yup, this ultimately is a matter of style. If you’re coming to R from another language, I encourage you to continue to use the = sign. Just know that <- is pretty common among R users.

Muddy Points

I feel like I don’t know what is unclear just yet as I am still very new to this concept.

I’m a very beginner, most stuff was unclear so I need time to practice.

My brain wants to know what every line of code is doing, otherwise I get hung up on trying to figure it out and can’t process what’s happening next. R feels like a very unintuitive language to me after using SAS for many years.

Still not super clear how Quarto works.

Great point, it’s hard to know what you need to know when you’ve encountered something brand new. Be patient and curious, and please reach out when you need help.

Muddy Points

The layout of Posit Cloud was a little confusing. The more we used it, the more I understood it, but it would have helped to have a little bit more of a tour of what all the windows are from the beginning.

If you haven’t already, I have recorded a video here that is a guided tour of the RStudio interface:

https://www.youtube.com/watch?v=oFmjHxl28H0

When to type into the console (bottom left) vs the source .qmd files (top left)

In general, you want to save your work, so I usually write my code in code chunks in a .qmd (Quarto Markdown file).

Ask Questions on Slido: https://bit.ly/ir-w2

Review of Exercise 1

Last week: Data types

  • Numeric: 18, -21, 65, 1.25
  • Character: “ATCG”, “Whatever”, “948-293-0000”
  • Logical: TRUE, FALSE

Learning Objectives for Today

By the end of today, you should be able to:

  • Explain how to construct vectors
  • Utilize explicit and implicit subsetting on vectors
  • Define what a data frame is and how it is related to vectors
  • Apply implicit subsetting to data.frames

Data structures

Data structures stores information about data types.

Vector is a ordered collection of a data type. Each element of a vector contains a data type, and all elements of a vector must be the same type, such as numeric, character, or logical.

So, you can have numeric vector, character vector, and logical vector.

Defining a vector

We use c() - the combine function to declare a vector

staff = c("chris", "ted", "jeff")
chrNum = c(2, 3, 1)

What happens when you mix data types in a vector? One of the data types is coerced to the other data type.

new_vector = c("chris", 1, 2)
new_vector
[1] "chris" "1"     "2"    

Using operations on vectors

You can use operations and functions on vectors.

chrNum = c(2, 3, 1)
chrNum3 = chrNum * 3
chrNum3 
[1] 6 9 3

Multiplication has a new meaning when used on a numeric vector and numeric data type! This is called operator overloading.

A lot of operations/functions in R are vectorized - you can apply a function to a single value or a whole vector. This will become very important later on.

😮

Operator overloading

How about numeric vector multiplied by numeric vector?

chrNum * c(2, 2, 0)
[1] 4 6 0

a numeric vector added to a character vector:

#chrNum + staff

Functions on vectors

How many elements are in this vector?

length(staff)
[1] 3

Subsetting vectors

We subset vectors using the bracket [ ] operation.

Inside the bracket is either a single numeric value or an a numerical indexing vector containing numerical values. They dictate which elements of the vector to return.

staff[2]
[1] "ted"
staff[c(1, 2)]
[1] "chris" "ted"  
small_staff = staff[c(1, 2)]
small_staff
[1] "chris" "ted"  

Subsetting vectors

Alternatively, instead of using numerical indexing vectors, we can use a logical indexing vector.

The logical indexing vector must be the same length as the vector to be subsetted, with TRUE indicating an element to keep, and FALSE indicating an element to drop.

staff[c(TRUE, FALSE, FALSE)]
[1] "chris"
staff[c(TRUE, TRUE, FALSE)]
[1] "chris" "ted"  
small_staff = staff[c(TRUE, TRUE, FALSE)]
small_staff
[1] "chris" "ted"  

Explicit subsetting

  • Explicit subsetting: Given a length 10 vector of people’s ages, and subset to the 1st, 3rd, and 9th elements.
age = c(89, 70, 64, 90, 66, 71, 55, 60, 30, 16)
age[c(1, 5, 9)]
[1] 89 66 30
age[c(TRUE, FALSE, FALSE, FALSE, TRUE, FALSE, FALSE, FALSE, TRUE, FALSE)]
[1] 89 66 30

Quick note about sequences

You can also declare a vector sequence using the : operator:

1:5
[1] 1 2 3 4 5

Implicit Subsetting

  • Implicit subsetting: Given a length 10 vector of people’s ages, and subset to elements greater than age 50.

We don’t know which elements to subset off the top of our head! If we know which elements are > 50, then we can give the elements for an explicit subset.

Use a comparison operator to create a logical indexing vector:

age > 50
 [1]  TRUE  TRUE  TRUE  TRUE  TRUE  TRUE  TRUE  TRUE FALSE FALSE

Can you guess what we do next?

age[age > 50]
[1] 89 70 64 90 66 71 55 60

Implicit subsetting steps

Subset a vector implicitly, in 3 steps:

  1. Come up with a criteria for subsetting: “I want to subset to values greater than 50”.
  1. Use a comparison operator to create a logical indexing vector that fits this criteria.
age > 50
 [1]  TRUE  TRUE  TRUE  TRUE  TRUE  TRUE  TRUE  TRUE FALSE FALSE
  1. Use this logical indexing vector to subset.
age[age > 50]
[1] 89 70 64 90 66 71 55 60

Alternatively,

idx = age > 50
age[idx]
[1] 89 70 64 90 66 71 55 60

Comparison operators:

< less than

<= less or equal than

> greater than

>= greater than or equal to

== equal to

!= not equal to

Subset staff to not have “chris” in it.

staff != "chris"
[1] FALSE  TRUE  TRUE
staff[staff != "chris"]
[1] "ted"  "jeff"

Ask Me Two Questions

https://bit.ly/ir-w2

data.frames

A data.frame is a table such that

  • each column is a vector
  • each column has a data type
  • order matters

This is the data structure that we will be working with for the rest of class.

load(url("https://github.com/fhdsl/Intro_to_R/raw/main/classroom_data/CCLE.RData"))
head(metadata)

data.frame Properties

Rows:

nrow(metadata)
[1] 1864

Columns:

ncol(metadata)
[1] 30

Dimension (rows x columns)

dim(metadata)
[1] 1864   30

Useful Tools for Peeking at data.frames

head(metadata)

View(metadata)

Column names of data.frames

The column name is a character vector that corresponds to the columns of the data.frame.

colnames(metadata)
 [1] "ModelID"                "PatientID"              "CellLineName"          
 [4] "StrippedCellLineName"   "Age"                    "SourceType"            
 [7] "SangerModelID"          "RRID"                   "DepmapModelType"       
[10] "AgeCategory"            "GrowthPattern"          "LegacyMolecularSubtype"
[13] "PrimaryOrMetastasis"    "SampleCollectionSite"   "Sex"                   
[16] "SourceDetail"           "LegacySubSubtype"       "CatalogNumber"         
[19] "CCLEName"               "COSMICID"               "PublicComments"        
[22] "WTSIMasterCellID"       "EngineeredModel"        "TreatmentStatus"       
[25] "OnboardedMedia"         "PlateCoating"           "OncotreeCode"          
[28] "OncotreeSubtype"        "OncotreePrimaryDisease" "OncotreeLineage"       

Subsetting a column from a data.frame

The dataframe$<column_name> operation selects for a column by its column name and returns the column as a vector:

metadata$OncotreeLineage
   [1] "Ovary/Fallopian Tube"      "Myeloid"                  
   [3] "Bowel"                     "Myeloid"                  
   [5] "Myeloid"                   "Myeloid"                  
   [7] "Bowel"                     "Skin"                     
   [9] "Bowel"                     "Bladder/Urinary Tract"    
  [11] "Lung"                      "Ovary/Fallopian Tube"     
  [13] "Skin"                      "Lung"                     
  [15] "Kidney"                    "Breast"                   
  [17] "Bladder/Urinary Tract"     "Breast"                   
  [19] "Lymphoid"                  "Lung"                     
  [21] "Pancreas"                  "Pancreas"                 
  [23] "Lymphoid"                  "CNS/Brain"                
  [25] "Bladder/Urinary Tract"     "CNS/Brain"                
  [27] "Breast"                    "Lung"                     
  [29] "Lung"                      "Pancreas"                 
  [31] "Lymphoid"                  "Lung"                     
  [33] "Myeloid"                   "Lung"                     
  [35] "CNS/Brain"                 "Soft Tissue"              
  [37] "Lymphoid"                  "Bone"                     
  [39] "CNS/Brain"                 "Bone"                     
  [41] "Pancreas"                  "Fibroblast"               
  [43] "Breast"                    "Myeloid"                  
  [45] "Kidney"                    "Esophagus/Stomach"        
  [47] "Ovary/Fallopian Tube"      "Kidney"                   
  [49] "Lymphoid"                  "Soft Tissue"              
  [51] "Bone"                      "Lymphoid"                 
  [53] "Soft Tissue"               "CNS/Brain"                
  [55] "Lymphoid"                  "Lymphoid"                 
  [57] "Thyroid"                   "Lymphoid"                 
  [59] "Pancreas"                  "Lymphoid"                 
  [61] "Lung"                      "Fibroblast"               
  [63] "Lung"                      "Myeloid"                  
  [65] "Lung"                      "CNS/Brain"                
  [67] "Lymphoid"                  "Lymphoid"                 
  [69] "Lymphoid"                  "Fibroblast"               
  [71] "Myeloid"                   "Lymphoid"                 
  [73] "Myeloid"                   "CNS/Brain"                
  [75] "Myeloid"                   "Lymphoid"                 
  [77] "Peripheral Nervous System" "Fibroblast"               
  [79] "Myeloid"                   "Myeloid"                  
  [81] "Bone"                      "Fibroblast"               
  [83] "Myeloid"                   "Pancreas"                 
  [85] "Pleura"                    "Bone"                     
  [87] "Fibroblast"                "Bowel"                    
  [89] "Prostate"                  "Ovary/Fallopian Tube"     
  [91] "Pleura"                    "Pancreas"                 
  [93] "Pancreas"                  "CNS/Brain"                
  [95] "Kidney"                    "Breast"                   
  [97] "CNS/Brain"                 "Peripheral Nervous System"
  [99] "Soft Tissue"               "Lymphoid"                 
 [101] "CNS/Brain"                 "Ovary/Fallopian Tube"     
 [103] "Lymphoid"                  "Lymphoid"                 
 [105] "Lymphoid"                  "Pancreas"                 
 [107] "Pancreas"                  "Lung"                     
 [109] "Esophagus/Stomach"         "Breast"                   
 [111] "Myeloid"                   "Myeloid"                  
 [113] "Pancreas"                  "Prostate"                 
 [115] "Ovary/Fallopian Tube"      "Breast"                   
 [117] "Pancreas"                  "Fibroblast"               
 [119] "Peripheral Nervous System" "Lung"                     
 [121] "Lymphoid"                  "Ovary/Fallopian Tube"     
 [123] "Lymphoid"                  "Fibroblast"               
 [125] "CNS/Brain"                 "Bladder/Urinary Tract"    
 [127] "CNS/Brain"                 "Lung"                     
 [129] "Lymphoid"                  "Fibroblast"               
 [131] "Ovary/Fallopian Tube"      "Soft Tissue"              
 [133] "Fibroblast"                "Fibroblast"               
 [135] "Peripheral Nervous System" "CNS/Brain"                
 [137] "Pancreas"                  "Pancreas"                 
 [139] "Lymphoid"                  "Biliary Tract"            
 [141] "Bladder/Urinary Tract"     "Lung"                     
 [143] "Esophagus/Stomach"         "Soft Tissue"              
 [145] "Myeloid"                   "Breast"                   
 [147] "Breast"                    "Peripheral Nervous System"
 [149] "Lung"                      "Lymphoid"                 
 [151] "CNS/Brain"                 "Pleura"                   
 [153] "Fibroblast"                "Pancreas"                 
 [155] "Lymphoid"                  "Lymphoid"                 
 [157] "Lymphoid"                  "Kidney"                   
 [159] "CNS/Brain"                 "Lung"                     
 [161] "Lymphoid"                  "Head and Neck"            
 [163] "Pancreas"                  "Fibroblast"               
 [165] "Myeloid"                   "Lymphoid"                 
 [167] "Myeloid"                   "Soft Tissue"              
 [169] "Prostate"                  "Kidney"                   
 [171] "CNS/Brain"                 "Uterus"                   
 [173] "Thyroid"                   "Fibroblast"               
 [175] "Lung"                      "Prostate"                 
 [177] "Pancreas"                  "Lung"                     
 [179] "Fibroblast"                "Head and Neck"            
 [181] "Ampulla of Vater"          "Lymphoid"                 
 [183] "Fibroblast"                "Fibroblast"               
 [185] "Lung"                      "Lung"                     
 [187] "Head and Neck"             "Kidney"                   
 [189] "Myeloid"                   "Thyroid"                  
 [191] "Uterus"                    "Lymphoid"                 
 [193] "Fibroblast"                "Myeloid"                  
 [195] "Breast"                    "Lymphoid"                 
 [197] "Myeloid"                   "Fibroblast"               
 [199] "CNS/Brain"                 "Soft Tissue"              
 [201] "Bowel"                     "Peripheral Nervous System"
 [203] "Lymphoid"                  "Pancreas"                 
 [205] "Lymphoid"                  "Head and Neck"            
 [207] "CNS/Brain"                 "Biliary Tract"            
 [209] "Bone"                      "CNS/Brain"                
 [211] "Breast"                    "Pancreas"                 
 [213] "Fibroblast"                "CNS/Brain"                
 [215] "Esophagus/Stomach"         "Liver"                    
 [217] "Myeloid"                   "Skin"                     
 [219] "Lymphoid"                  "Liver"                    
 [221] "Pancreas"                  "Breast"                   
 [223] "Fibroblast"                "Esophagus/Stomach"        
 [225] "Lymphoid"                  "Peripheral Nervous System"
 [227] "Head and Neck"             "Fibroblast"               
 [229] "Fibroblast"                "CNS/Brain"                
 [231] "CNS/Brain"                 "Lymphoid"                 
 [233] "Kidney"                    "Pancreas"                 
 [235] "Bowel"                     "Ovary/Fallopian Tube"     
 [237] "Head and Neck"             "Esophagus/Stomach"        
 [239] "Fibroblast"                "Myeloid"                  
 [241] "Bladder/Urinary Tract"     "Pancreas"                 
 [243] "CNS/Brain"                 "Lymphoid"                 
 [245] "Kidney"                    "Esophagus/Stomach"        
 [247] "Breast"                    "Bowel"                    
 [249] "Kidney"                    "Lung"                     
 [251] "Bowel"                     "Bowel"                    
 [253] "Head and Neck"             "Esophagus/Stomach"        
 [255] "Ovary/Fallopian Tube"      "Lung"                     
 [257] "Breast"                    "Peripheral Nervous System"
 [259] "Peripheral Nervous System" "Lung"                     
 [261] "Kidney"                    "Myeloid"                  
 [263] "Lung"                      "Pancreas"                 
 [265] "Pancreas"                  "Lymphoid"                 
 [267] "Biliary Tract"             "CNS/Brain"                
 [269] "Pancreas"                  "Lymphoid"                 
 [271] "Kidney"                    "CNS/Brain"                
 [273] "Skin"                      "Fibroblast"               
 [275] "Breast"                    "Breast"                   
 [277] "Ovary/Fallopian Tube"      "Bone"                     
 [279] "Ovary/Fallopian Tube"      "Pancreas"                 
 [281] "Lung"                      "CNS/Brain"                
 [283] "Fibroblast"                "Lymphoid"                 
 [285] "Bowel"                     "Lymphoid"                 
 [287] "Breast"                    "CNS/Brain"                
 [289] "Lung"                      "Ovary/Fallopian Tube"     
 [291] "Lung"                      "Uterus"                   
 [293] "Myeloid"                   "Myeloid"                  
 [295] "Bowel"                     "Lung"                     
 [297] "Lung"                      "Myeloid"                  
 [299] "Kidney"                    "Myeloid"                  
 [301] "Uterus"                    "Esophagus/Stomach"        
 [303] "Skin"                      "Esophagus/Stomach"        
 [305] "Fibroblast"                "Pancreas"                 
 [307] "Ovary/Fallopian Tube"      "Lung"                     
 [309] "Peripheral Nervous System" "Lung"                     
 [311] "Peripheral Nervous System" "Kidney"                   
 [313] "Lung"                      "Lymphoid"                 
 [315] "Liver"                     "Kidney"                   
 [317] "Esophagus/Stomach"         "Pleura"                   
 [319] "Pancreas"                  "Myeloid"                  
 [321] "Skin"                      "CNS/Brain"                
 [323] "Ovary/Fallopian Tube"      "Esophagus/Stomach"        
 [325] "Myeloid"                   "Lung"                     
 [327] "CNS/Brain"                 "CNS/Brain"                
 [329] "Breast"                    "Pleura"                   
 [331] "Pancreas"                  "Ovary/Fallopian Tube"     
 [333] "Lymphoid"                  "Pleura"                   
 [335] "Myeloid"                   "Lung"                     
 [337] "Lymphoid"                  "Lung"                     
 [339] "Fibroblast"                "Peripheral Nervous System"
 [341] "Bowel"                     "Lung"                     
 [343] "Esophagus/Stomach"         "Peripheral Nervous System"
 [345] "Lymphoid"                  "Pancreas"                 
 [347] "Skin"                      "Breast"                   
 [349] "Bowel"                     "Esophagus/Stomach"        
 [351] "Breast"                    "Esophagus/Stomach"        
 [353] "Pancreas"                  "Lung"                     
 [355] "Esophagus/Stomach"         "Lymphoid"                 
 [357] "Lung"                      "Bone"                     
 [359] "Bowel"                     "Liver"                    
 [361] "Myeloid"                   "Lymphoid"                 
 [363] "Bone"                      "Lymphoid"                 
 [365] "Peripheral Nervous System" "Pleura"                   
 [367] "CNS/Brain"                 "Myeloid"                  
 [369] "CNS/Brain"                 "Lymphoid"                 
 [371] "Lymphoid"                  "Myeloid"                  
 [373] "Breast"                    "Kidney"                   
 [375] "CNS/Brain"                 "Ampulla of Vater"         
 [377] "Lung"                      "Lung"                     
 [379] "Lymphoid"                  "Bowel"                    
 [381] "Lung"                      "Esophagus/Stomach"        
 [383] "Bladder/Urinary Tract"     "Kidney"                   
 [385] "Myeloid"                   "Myeloid"                  
 [387] "Lymphoid"                  "CNS/Brain"                
 [389] "Lung"                      "Bone"                     
 [391] "Lung"                      "Liver"                    
 [393] "Lung"                      "Lung"                     
 [395] "Bladder/Urinary Tract"     "Uterus"                   
 [397] "Lymphoid"                  "Lung"                     
 [399] "Bowel"                     "Skin"                     
 [401] "Lymphoid"                  "Bowel"                    
 [403] "Skin"                      "Lymphoid"                 
 [405] "Myeloid"                   "Uterus"                   
 [407] "Esophagus/Stomach"         "Ovary/Fallopian Tube"     
 [409] "Bone"                      "Kidney"                   
 [411] "Bowel"                     "Fibroblast"               
 [413] "Lung"                      "Head and Neck"            
 [415] "Lung"                      "Pancreas"                 
 [417] "Bone"                      "Lymphoid"                 
 [419] "Liver"                     "Bowel"                    
 [421] "Liver"                     "Skin"                     
 [423] "Bone"                      "Skin"                     
 [425] "Lymphoid"                  "Esophagus/Stomach"        
 [427] "Kidney"                    "Kidney"                   
 [429] "Ovary/Fallopian Tube"      "Lung"                     
 [431] "Myeloid"                   "Kidney"                   
 [433] "Lung"                      "Uterus"                   
 [435] "Lymphoid"                  "CNS/Brain"                
 [437] "Lung"                      "Myeloid"                  
 [439] "Lymphoid"                  "Skin"                     
 [441] "Lung"                      "Ovary/Fallopian Tube"     
 [443] "Lung"                      "CNS/Brain"                
 [445] "Peripheral Nervous System" "Lung"                     
 [447] "Lung"                      "Uterus"                   
 [449] "Skin"                      "Lung"                     
 [451] "Esophagus/Stomach"         "Lymphoid"                 
 [453] "Lung"                      "CNS/Brain"                
 [455] "Thyroid"                   "Kidney"                   
 [457] "Skin"                      "Kidney"                   
 [459] "Ovary/Fallopian Tube"      "Biliary Tract"            
 [461] "Myeloid"                   "Lung"                     
 [463] "CNS/Brain"                 "Skin"                     
 [465] "Esophagus/Stomach"         "Bowel"                    
 [467] "Pancreas"                  "CNS/Brain"                
 [469] "Bowel"                     "Liver"                    
 [471] "Head and Neck"             "Bladder/Urinary Tract"    
 [473] "Liver"                     "Liver"                    
 [475] "Skin"                      "Liver"                    
 [477] "CNS/Brain"                 "Liver"                    
 [479] "Lung"                      "Lung"                     
 [481] "Liver"                     "Kidney"                   
 [483] "Esophagus/Stomach"         "Bladder/Urinary Tract"    
 [485] "Myeloid"                   "Esophagus/Stomach"        
 [487] "Bowel"                     "Cervix"                   
 [489] "Bowel"                     "Lymphoid"                 
 [491] "Liver"                     "Ovary/Fallopian Tube"     
 [493] "Kidney"                    "Lung"                     
 [495] "Myeloid"                   "Bone"                     
 [497] "Head and Neck"             "Bowel"                    
 [499] "Pancreas"                  "Head and Neck"            
 [501] "CNS/Brain"                 "Soft Tissue"              
 [503] "Lung"                      "Esophagus/Stomach"        
 [505] "Lung"                      "Lymphoid"                 
 [507] "Lung"                      "Lung"                     
 [509] "Lymphoid"                  "Kidney"                   
 [511] "Lung"                      "Lung"                     
 [513] "Bone"                      "Pancreas"                 
 [515] "Head and Neck"             "Lymphoid"                 
 [517] "Ovary/Fallopian Tube"      "Lung"                     
 [519] "Bladder/Urinary Tract"     "Lung"                     
 [521] "Ovary/Fallopian Tube"      "Lung"                     
 [523] "Fibroblast"                "Ovary/Fallopian Tube"     
 [525] "Lung"                      "Fibroblast"               
 [527] "Lung"                      "Fibroblast"               
 [529] "Bowel"                     "Kidney"                   
 [531] "Lymphoid"                  "Pancreas"                 
 [533] "Breast"                    "Liver"                    
 [535] "Bowel"                     "Fibroblast"               
 [537] "Fibroblast"                "Lymphoid"                 
 [539] "Ovary/Fallopian Tube"      "CNS/Brain"                
 [541] "Esophagus/Stomach"         "Bladder/Urinary Tract"    
 [543] "Head and Neck"             "Bladder/Urinary Tract"    
 [545] "Head and Neck"             "Head and Neck"            
 [547] "Skin"                      "Myeloid"                  
 [549] "Bowel"                     "Lung"                     
 [551] "Breast"                    "Kidney"                   
 [553] "Cervix"                    "Myeloid"                  
 [555] "CNS/Brain"                 "Lung"                     
 [557] "Esophagus/Stomach"         "Esophagus/Stomach"        
 [559] "Lung"                      "Lung"                     
 [561] "Lymphoid"                  "Bowel"                    
 [563] "Bladder/Urinary Tract"     "Lymphoid"                 
 [565] "Breast"                    "Pleura"                   
 [567] "CNS/Brain"                 "CNS/Brain"                
 [569] "Skin"                      "Breast"                   
 [571] "Ovary/Fallopian Tube"      "Lung"                     
 [573] "Lymphoid"                  "Liver"                    
 [575] "Lung"                      "Skin"                     
 [577] "Skin"                      "Esophagus/Stomach"        
 [579] "Skin"                      "Lymphoid"                 
 [581] "Ovary/Fallopian Tube"      "Lung"                     
 [583] "Lung"                      "Lung"                     
 [585] "Lymphoid"                  "Lung"                     
 [587] "Lung"                      "CNS/Brain"                
 [589] "CNS/Brain"                 "Bladder/Urinary Tract"    
 [591] "Lung"                      "CNS/Brain"                
 [593] "Lung"                      "CNS/Brain"                
 [595] "Lymphoid"                  "Pancreas"                 
 [597] "Kidney"                    "Pancreas"                 
 [599] "Myeloid"                   "Lung"                     
 [601] "Myeloid"                   "Esophagus/Stomach"        
 [603] "Head and Neck"             "Soft Tissue"              
 [605] "Ovary/Fallopian Tube"      "CNS/Brain"                
 [607] "Lung"                      "Lymphoid"                 
 [609] "Lymphoid"                  "Bone"                     
 [611] "Skin"                      "Skin"                     
 [613] "Esophagus/Stomach"         "Ovary/Fallopian Tube"     
 [615] "Head and Neck"             "Head and Neck"            
 [617] "Liver"                     "Breast"                   
 [619] "CNS/Brain"                 "CNS/Brain"                
 [621] "Breast"                    "Liver"                    
 [623] "Lymphoid"                  "Lung"                     
 [625] "Lung"                      "CNS/Brain"                
 [627] "Head and Neck"             "CNS/Brain"                
 [629] "Skin"                      "Esophagus/Stomach"        
 [631] "CNS/Brain"                 "Ovary/Fallopian Tube"     
 [633] "Lymphoid"                  "Esophagus/Stomach"        
 [635] "Lung"                      "Lung"                     
 [637] "Skin"                      "Myeloid"                  
 [639] "Breast"                    "Breast"                   
 [641] "Skin"                      "Pleura"                   
 [643] "Ovary/Fallopian Tube"      "Esophagus/Stomach"        
 [645] "Pleura"                    "Kidney"                   
 [647] "Skin"                      "Bowel"                    
 [649] "Pancreas"                  "Lymphoid"                 
 [651] "Lymphoid"                  "CNS/Brain"                
 [653] "Lymphoid"                  "Ovary/Fallopian Tube"     
 [655] "Lymphoid"                  "Lung"                     
 [657] "Lymphoid"                  "Skin"                     
 [659] "Lung"                      "Ovary/Fallopian Tube"     
 [661] "Lymphoid"                  "Lung"                     
 [663] "Lung"                      "Lung"                     
 [665] "Breast"                    "Lung"                     
 [667] "Lung"                      "Liver"                    
 [669] "Lung"                      "CNS/Brain"                
 [671] "Esophagus/Stomach"         "Lung"                     
 [673] "CNS/Brain"                 "Lung"                     
 [675] "Esophagus/Stomach"         "Esophagus/Stomach"        
 [677] "Bowel"                     "Lung"                     
 [679] "Head and Neck"             "Bowel"                    
 [681] "Kidney"                    "Pancreas"                 
 [683] "Liver"                     "Lymphoid"                 
 [685] "Ovary/Fallopian Tube"      "Soft Tissue"              
 [687] "Lung"                      "Breast"                   
 [689] "Head and Neck"             "Esophagus/Stomach"        
 [691] "Esophagus/Stomach"         "Lung"                     
 [693] "Ovary/Fallopian Tube"      "Lymphoid"                 
 [695] "Lung"                      "Breast"                   
 [697] "Lung"                      "Ovary/Fallopian Tube"     
 [699] "Lymphoid"                  "Lung"                     
 [701] "Ovary/Fallopian Tube"      "Lung"                     
 [703] "Lung"                      "Lymphoid"                 
 [705] "Bowel"                     "Kidney"                   
 [707] "Bowel"                     "Breast"                   
 [709] "Lung"                      "Ovary/Fallopian Tube"     
 [711] "Lymphoid"                  "Head and Neck"            
 [713] "Thyroid"                   "Esophagus/Stomach"        
 [715] "Lung"                      "Ovary/Fallopian Tube"     
 [717] "Bladder/Urinary Tract"     "Breast"                   
 [719] "Bowel"                     "Head and Neck"            
 [721] "Bladder/Urinary Tract"     "Breast"                   
 [723] "Esophagus/Stomach"         "Lung"                     
 [725] "Lymphoid"                  "Lung"                     
 [727] "Skin"                      "Lung"                     
 [729] "Head and Neck"             "Lung"                     
 [731] "Liver"                     "Head and Neck"            
 [733] "Esophagus/Stomach"         "Lung"                     
 [735] "CNS/Brain"                 "Liver"                    
 [737] "Head and Neck"             "Bladder/Urinary Tract"    
 [739] "Fibroblast"                "Lung"                     
 [741] "Lung"                      "Lymphoid"                 
 [743] "Esophagus/Stomach"         "Lung"                     
 [745] "Bone"                      "Lung"                     
 [747] "Skin"                      "Myeloid"                  
 [749] "Lung"                      "Bladder/Urinary Tract"    
 [751] "Lymphoid"                  "Breast"                   
 [753] "CNS/Brain"                 "Lung"                     
 [755] "Esophagus/Stomach"         "Breast"                   
 [757] "CNS/Brain"                 "Esophagus/Stomach"        
 [759] "Head and Neck"             "Lymphoid"                 
 [761] "Esophagus/Stomach"         "Skin"                     
 [763] "Lung"                      "Lung"                     
 [765] "Breast"                    "Lung"                     
 [767] "Myeloid"                   "Head and Neck"            
 [769] "Soft Tissue"               "Lymphoid"                 
 [771] "Lung"                      "Lung"                     
 [773] "CNS/Brain"                 "Esophagus/Stomach"        
 [775] "Head and Neck"             "Lung"                     
 [777] "Lung"                      "Lung"                     
 [779] "Lymphoid"                  "Breast"                   
 [781] "Esophagus/Stomach"         "Lung"                     
 [783] "Lymphoid"                  "Lung"                     
 [785] "Skin"                      "Lung"                     
 [787] "Lung"                      "Lung"                     
 [789] "Kidney"                    "Esophagus/Stomach"        
 [791] "Head and Neck"             "Lymphoid"                 
 [793] "Ovary/Fallopian Tube"      "Fibroblast"               
 [795] "Bowel"                     "Skin"                     
 [797] "Lung"                      "Skin"                     
 [799] "Bladder/Urinary Tract"     "Lung"                     
 [801] "Peripheral Nervous System" "Skin"                     
 [803] "Lymphoid"                  "CNS/Brain"                
 [805] "Biliary Tract"             "Esophagus/Stomach"        
 [807] "Skin"                      "Ovary/Fallopian Tube"     
 [809] "Skin"                      "Lung"                     
 [811] "Skin"                      "Lymphoid"                 
 [813] "Lung"                      "Lymphoid"                 
 [815] "Breast"                    "CNS/Brain"                
 [817] "Bowel"                     "Lymphoid"                 
 [819] "Skin"                      "Esophagus/Stomach"        
 [821] "Esophagus/Stomach"         "Lung"                     
 [823] "Lung"                      "Skin"                     
 [825] "Breast"                    "Lymphoid"                 
 [827] "Lung"                      "Uterus"                   
 [829] "Head and Neck"             "Soft Tissue"              
 [831] "Bladder/Urinary Tract"     "Soft Tissue"              
 [833] "Head and Neck"             "Lung"                     
 [835] "Lymphoid"                  "Bladder/Urinary Tract"    
 [837] "Lung"                      "Lung"                     
 [839] "Bowel"                     "Lung"                     
 [841] "Lung"                      "Lung"                     
 [843] "Head and Neck"             "Esophagus/Stomach"        
 [845] "Liver"                     "Breast"                   
 [847] "Fibroblast"                "Lung"                     
 [849] "Lung"                      "Lung"                     
 [851] "Lymphoid"                  "Esophagus/Stomach"        
 [853] "Breast"                    "Breast"                   
 [855] "Lung"                      "Breast"                   
 [857] "Lung"                      "Lung"                     
 [859] "Bladder/Urinary Tract"     "CNS/Brain"                
 [861] "Uterus"                    "Esophagus/Stomach"        
 [863] "Lung"                      "Lung"                     
 [865] "Lung"                      "Lung"                     
 [867] "Lung"                      "Lung"                     
 [869] "Lung"                      "Esophagus/Stomach"        
 [871] "Lymphoid"                  "Lung"                     
 [873] "Breast"                    "Lymphoid"                 
 [875] "Lung"                      "Uterus"                   
 [877] "Esophagus/Stomach"         "Skin"                     
 [879] "Skin"                      "CNS/Brain"                
 [881] "Skin"                      "Ovary/Fallopian Tube"     
 [883] "Lung"                      "CNS/Brain"                
 [885] "Lung"                      "Lymphoid"                 
 [887] "Lung"                      "Lung"                     
 [889] "Lung"                      "Lung"                     
 [891] "Lung"                      "Bowel"                    
 [893] "Bladder/Urinary Tract"     "Thyroid"                  
 [895] "Esophagus/Stomach"         "Skin"                     
 [897] "Lung"                      "Lung"                     
 [899] "Breast"                    "Thyroid"                  
 [901] "Lung"                      "Bladder/Urinary Tract"    
 [903] "Ovary/Fallopian Tube"      "Kidney"                   
 [905] "Esophagus/Stomach"         "Uterus"                   
 [907] "Breast"                    "Esophagus/Stomach"        
 [909] "Lung"                      "Uterus"                   
 [911] "Lymphoid"                  "Skin"                     
 [913] "Lung"                      "Esophagus/Stomach"        
 [915] "Lymphoid"                  "Esophagus/Stomach"        
 [917] "Myeloid"                   "Lung"                     
 [919] "Lymphoid"                  "Lymphoid"                 
 [921] "Lung"                      "Lung"                     
 [923] "Bowel"                     "Breast"                   
 [925] "Uterus"                    "Lung"                     
 [927] "Breast"                    "Skin"                     
 [929] "Esophagus/Stomach"         "Pancreas"                 
 [931] "Breast"                    "Bowel"                    
 [933] "Ovary/Fallopian Tube"      "Lymphoid"                 
 [935] "Lymphoid"                  "Uterus"                   
 [937] "Uterus"                    "Uterus"                   
 [939] "Lymphoid"                  "Bowel"                    
 [941] "Lymphoid"                  "Lung"                     
 [943] "Uterus"                    "Ovary/Fallopian Tube"     
 [945] "Esophagus/Stomach"         "Esophagus/Stomach"        
 [947] "Bowel"                     "Lung"                     
 [949] "Prostate"                  "Lymphoid"                 
 [951] "Uterus"                    "Bowel"                    
 [953] "Prostate"                  "Bowel"                    
 [955] "Bowel"                     "Bowel"                    
 [957] "Lymphoid"                  "Uterus"                   
 [959] "Ovary/Fallopian Tube"      "Bowel"                    
 [961] "Lymphoid"                  "Uterus"                   
 [963] "Ovary/Fallopian Tube"      "Bowel"                    
 [965] "Skin"                      "Bowel"                    
 [967] "Bowel"                     "Bowel"                    
 [969] "Uterus"                    "Bladder/Urinary Tract"    
 [971] "Uterus"                    "Lung"                     
 [973] "Biliary Tract"             "Prostate"                 
 [975] "Uterus"                    "Prostate"                 
 [977] "Lung"                      "Lymphoid"                 
 [979] "Bowel"                     "Myeloid"                  
 [981] "Uterus"                    "Bowel"                    
 [983] "Bowel"                     "Skin"                     
 [985] "Uterus"                    "Bowel"                    
 [987] "Uterus"                    "Bowel"                    
 [989] "Head and Neck"             "Uterus"                   
 [991] "Uterus"                    "Lymphoid"                 
 [993] "Uterus"                    "Bowel"                    
 [995] "Bowel"                     "Bowel"                    
 [997] "CNS/Brain"                 "Bone"                     
 [999] "Skin"                      "Bone"                     
[1001] "Bone"                      "Bone"                     
[1003] "Bone"                      "Bowel"                    
[1005] "CNS/Brain"                 "Cervix"                   
[1007] "Fibroblast"                "CNS/Brain"                
[1009] "Liver"                     "Bone"                     
[1011] "Head and Neck"             "Skin"                     
[1013] "CNS/Brain"                 "Bone"                     
[1015] "Bone"                      "CNS/Brain"                
[1017] "Bone"                      "CNS/Brain"                
[1019] "Bone"                      "Bone"                     
[1021] "Myeloid"                   "Myeloid"                  
[1023] "Bone"                      "Bowel"                    
[1025] "Skin"                      "Uterus"                   
[1027] "Lymphoid"                  "Skin"                     
[1029] "Skin"                      "Lung"                     
[1031] "Ovary/Fallopian Tube"      "Lung"                     
[1033] "Soft Tissue"               "CNS/Brain"                
[1035] "CNS/Brain"                 "CNS/Brain"                
[1037] "CNS/Brain"                 "Lymphoid"                 
[1039] "CNS/Brain"                 "Lymphoid"                 
[1041] "Bowel"                     "Ovary/Fallopian Tube"     
[1043] "Lymphoid"                  "Breast"                   
[1045] "Bone"                      "CNS/Brain"                
[1047] "Lymphoid"                  "Cervix"                   
[1049] "Pancreas"                  "Lung"                     
[1051] "Lung"                      "Bowel"                    
[1053] "Bowel"                     "Cervix"                   
[1055] "Kidney"                    "Lung"                     
[1057] "Liver"                     "Head and Neck"            
[1059] "Bowel"                     "Fibroblast"               
[1061] "Bone"                      "Soft Tissue"              
[1063] "Lymphoid"                  "Pancreas"                 
[1065] "CNS/Brain"                 "Lymphoid"                 
[1067] "Pancreas"                  "Lymphoid"                 
[1069] "Pancreas"                  "Kidney"                   
[1071] "Lymphoid"                  "Lung"                     
[1073] "CNS/Brain"                 "Lymphoid"                 
[1075] "Lymphoid"                  "Skin"                     
[1077] "Skin"                      "CNS/Brain"                
[1079] "CNS/Brain"                 "Lymphoid"                 
[1081] "CNS/Brain"                 "Myeloid"                  
[1083] "Lymphoid"                  "Skin"                     
[1085] "Lymphoid"                  "Lymphoid"                 
[1087] "Lung"                      "Lung"                     
[1089] "Lung"                      "CNS/Brain"                
[1091] "Lymphoid"                  "Ovary/Fallopian Tube"     
[1093] "Ovary/Fallopian Tube"      "Lymphoid"                 
[1095] "Lymphoid"                  "Lymphoid"                 
[1097] "Bone"                      "Ovary/Fallopian Tube"     
[1099] "Lymphoid"                  "Kidney"                   
[1101] "Soft Tissue"               "Skin"                     
[1103] "Pancreas"                  "CNS/Brain"                
[1105] "Kidney"                    "Lymphoid"                 
[1107] "Bladder/Urinary Tract"     "Soft Tissue"              
[1109] "Peripheral Nervous System" "Soft Tissue"              
[1111] "Skin"                      "Bone"                     
[1113] "Bone"                      "Kidney"                   
[1115] "Soft Tissue"               "Lymphoid"                 
[1117] "CNS/Brain"                 "Bowel"                    
[1119] "Kidney"                    "CNS/Brain"                
[1121] "Lymphoid"                  "Bone"                     
[1123] "Bone"                      "Fibroblast"               
[1125] "Kidney"                    "Kidney"                   
[1127] "CNS/Brain"                 "CNS/Brain"                
[1129] "CNS/Brain"                 "Kidney"                   
[1131] "Kidney"                    "Head and Neck"            
[1133] "Head and Neck"             "Head and Neck"            
[1135] "Myeloid"                   "CNS/Brain"                
[1137] "Lung"                      "Lung"                     
[1139] "Skin"                      "Breast"                   
[1141] "Soft Tissue"               "Soft Tissue"              
[1143] "Soft Tissue"               "Soft Tissue"              
[1145] "Soft Tissue"               "Ovary/Fallopian Tube"     
[1147] "Ovary/Fallopian Tube"      "Soft Tissue"              
[1149] "Bone"                      "Bone"                     
[1151] "CNS/Brain"                 "Eye"                      
[1153] "Peripheral Nervous System" "Peripheral Nervous System"
[1155] "Peripheral Nervous System" "Peripheral Nervous System"
[1157] "Thyroid"                   "Thyroid"                  
[1159] "Kidney"                    "Liver"                    
[1161] "Thyroid"                   "Soft Tissue"              
[1163] "Skin"                      "CNS/Brain"                
[1165] "Head and Neck"             "Head and Neck"            
[1167] "Cervix"                    "Cervix"                   
[1169] "Cervix"                    "Cervix"                   
[1171] "Peripheral Nervous System" "Skin"                     
[1173] "Ovary/Fallopian Tube"      "Cervix"                   
[1175] "Peripheral Nervous System" "Bowel"                    
[1177] "Head and Neck"             "Head and Neck"            
[1179] "Thyroid"                   "Pancreas"                 
[1181] "Peripheral Nervous System" "Peripheral Nervous System"
[1183] "Thyroid"                   "Breast"                   
[1185] "Breast"                    "Cervix"                   
[1187] "Cervix"                    "Lung"                     
[1189] "Lung"                      "Lung"                     
[1191] "Lung"                      "Peripheral Nervous System"
[1193] "Peripheral Nervous System" "Esophagus/Stomach"        
[1195] "Ovary/Fallopian Tube"      "Ovary/Fallopian Tube"     
[1197] "Ovary/Fallopian Tube"      "Ovary/Fallopian Tube"     
[1199] "Pancreas"                  "Pancreas"                 
[1201] "Pancreas"                  "Pancreas"                 
[1203] "Pancreas"                  "Pancreas"                 
[1205] "Pancreas"                  "Prostate"                 
[1207] "Thyroid"                   "Head and Neck"            
[1209] "Lung"                      "Breast"                   
[1211] "Breast"                    "Breast"                   
[1213] "Breast"                    "Breast"                   
[1215] "Breast"                    "Breast"                   
[1217] "Breast"                    "Breast"                   
[1219] "Breast"                    "Kidney"                   
[1221] "Bowel"                     "Vulva/Vagina"             
[1223] "Adrenal Gland"             "Cervix"                   
[1225] "Ovary/Fallopian Tube"      "Bladder/Urinary Tract"    
[1227] "Bladder/Urinary Tract"     "Bladder/Urinary Tract"    
[1229] "Bladder/Urinary Tract"     "Bladder/Urinary Tract"    
[1231] "Bladder/Urinary Tract"     "Bladder/Urinary Tract"    
[1233] "Bladder/Urinary Tract"     "Bladder/Urinary Tract"    
[1235] "Bladder/Urinary Tract"     "Lung"                     
[1237] "Ovary/Fallopian Tube"      "Breast"                   
[1239] "Eye"                       "Prostate"                 
[1241] "Bone"                      "Bone"                     
[1243] "Soft Tissue"               "Eye"                      
[1245] "Skin"                      "Thyroid"                  
[1247] "Lymphoid"                  "Cervix"                   
[1249] "Lymphoid"                  "Prostate"                 
[1251] "Bowel"                     "Bowel"                    
[1253] "Bowel"                     "Bowel"                    
[1255] "Bowel"                     "Bowel"                    
[1257] "Peripheral Nervous System" "Lymphoid"                 
[1259] "Lymphoid"                  "Lung"                     
[1261] "Lung"                      "Biliary Tract"            
[1263] "Uterus"                    "Esophagus/Stomach"        
[1265] "Esophagus/Stomach"         "Lymphoid"                 
[1267] "Esophagus/Stomach"         "Head and Neck"            
[1269] "Head and Neck"             "Head and Neck"            
[1271] "Cervix"                    "Breast"                   
[1273] "Cervix"                    "Cervix"                   
[1275] "Uterus"                    "Uterus"                   
[1277] "Bone"                      "Lymphoid"                 
[1279] "Skin"                      "Skin"                     
[1281] "Skin"                      "Skin"                     
[1283] "Cervix"                    "Bone"                     
[1285] "Thyroid"                   "Uterus"                   
[1287] "Uterus"                    "Kidney"                   
[1289] "Lymphoid"                  "Biliary Tract"            
[1291] "Biliary Tract"             "Lymphoid"                 
[1293] "Soft Tissue"               "Lymphoid"                 
[1295] "Head and Neck"             "Head and Neck"            
[1297] "Esophagus/Stomach"         "Pleura"                   
[1299] "Peripheral Nervous System" "Lung"                     
[1301] "Skin"                      "Skin"                     
[1303] "Skin"                      "Eye"                      
[1305] "Pleura"                    "Pleura"                   
[1307] "Pleura"                    "Pleura"                   
[1309] "Pleura"                    "Pleura"                   
[1311] "Pleura"                    "Pleura"                   
[1313] "Skin"                      "Skin"                     
[1315] "Skin"                      "Skin"                     
[1317] "Skin"                      "Skin"                     
[1319] "Myeloid"                   "Myeloid"                  
[1321] "Myeloid"                   "Testis"                   
[1323] "Lung"                      "Lung"                     
[1325] "Peripheral Nervous System" "CNS/Brain"                
[1327] "CNS/Brain"                 "Biliary Tract"            
[1329] "CNS/Brain"                 "CNS/Brain"                
[1331] "CNS/Brain"                 "CNS/Brain"                
[1333] "Myeloid"                   "Lymphoid"                 
[1335] "Lymphoid"                  "Myeloid"                  
[1337] "Biliary Tract"             "CNS/Brain"                
[1339] "CNS/Brain"                 "CNS/Brain"                
[1341] "Head and Neck"             "Head and Neck"            
[1343] "Prostate"                  "Ovary/Fallopian Tube"     
[1345] "Ovary/Fallopian Tube"      "Ovary/Fallopian Tube"     
[1347] "Lymphoid"                  "Lymphoid"                 
[1349] "Lymphoid"                  "Lymphoid"                 
[1351] "Head and Neck"             "Lymphoid"                 
[1353] "Skin"                      "Myeloid"                  
[1355] "Prostate"                  "Prostate"                 
[1357] "Cervix"                    "Cervix"                   
[1359] "Cervix"                    "Esophagus/Stomach"        
[1361] "Esophagus/Stomach"         "Uterus"                   
[1363] "Myeloid"                   "Esophagus/Stomach"        
[1365] "Testis"                    "Lymphoid"                 
[1367] "CNS/Brain"                 "Biliary Tract"            
[1369] "Peripheral Nervous System" "Head and Neck"            
[1371] "Lymphoid"                  "Lymphoid"                 
[1373] "Lymphoid"                  "Kidney"                   
[1375] "Kidney"                    "Head and Neck"            
[1377] "Head and Neck"             "Head and Neck"            
[1379] "Head and Neck"             "Head and Neck"            
[1381] "Head and Neck"             "Head and Neck"            
[1383] "Head and Neck"             "Soft Tissue"              
[1385] "Lymphoid"                  "Skin"                     
[1387] "Lymphoid"                  "Lymphoid"                 
[1389] "CNS/Brain"                 "Bone"                     
[1391] "Bone"                      "Peripheral Nervous System"
[1393] "Ovary/Fallopian Tube"      "Lymphoid"                 
[1395] "Lymphoid"                  "Lymphoid"                 
[1397] "Lymphoid"                  "Soft Tissue"              
[1399] "Soft Tissue"               "Soft Tissue"              
[1401] "Soft Tissue"               "Soft Tissue"              
[1403] "Soft Tissue"               "Fibroblast"               
[1405] "Bowel"                     "Soft Tissue"              
[1407] "Soft Tissue"               "Soft Tissue"              
[1409] "Soft Tissue"               "Soft Tissue"              
[1411] "Soft Tissue"               "Soft Tissue"              
[1413] "Soft Tissue"               "Soft Tissue"              
[1415] "Bone"                      "Bone"                     
[1417] "Breast"                    "Breast"                   
[1419] "Bowel"                     "Breast"                   
[1421] "Biliary Tract"             "Biliary Tract"            
[1423] "Biliary Tract"             "Biliary Tract"            
[1425] "Biliary Tract"             "Biliary Tract"            
[1427] "Biliary Tract"             "Biliary Tract"            
[1429] "Biliary Tract"             "Biliary Tract"            
[1431] "Biliary Tract"             "Biliary Tract"            
[1433] "Biliary Tract"             "Biliary Tract"            
[1435] "Biliary Tract"             "Liver"                    
[1437] "Biliary Tract"             "Biliary Tract"            
[1439] "Biliary Tract"             "Biliary Tract"            
[1441] "Ampulla of Vater"          "Biliary Tract"            
[1443] "Biliary Tract"             "Lung"                     
[1445] "Biliary Tract"             "Biliary Tract"            
[1447] "Biliary Tract"             "Skin"                     
[1449] "Skin"                      "Pleura"                   
[1451] "Skin"                      "Skin"                     
[1453] "Skin"                      "Ovary/Fallopian Tube"     
[1455] "Pleura"                    "Lymphoid"                 
[1457] "Biliary Tract"             "Pancreas"                 
[1459] "Skin"                      "Skin"                     
[1461] "Skin"                      "Skin"                     
[1463] "Skin"                      "Eye"                      
[1465] "Eye"                       "Eye"                      
[1467] "Eye"                       "Eye"                      
[1469] "Eye"                       "Cervix"                   
[1471] "Cervix"                    "Uterus"                   
[1473] "Ampulla of Vater"          "Bowel"                    
[1475] "Bowel"                     "Uterus"                   
[1477] "Uterus"                    "Head and Neck"            
[1479] "Lung"                      "Ovary/Fallopian Tube"     
[1481] "Pancreas"                  "Vulva/Vagina"             
[1483] "Thyroid"                   "Head and Neck"            
[1485] "Head and Neck"             "Head and Neck"            
[1487] "Head and Neck"             "Uterus"                   
[1489] "Soft Tissue"               "Lung"                     
[1491] "Lung"                      "Lymphoid"                 
[1493] "Lymphoid"                  "Lymphoid"                 
[1495] "Myeloid"                   "Lymphoid"                 
[1497] "Peripheral Nervous System" "Peripheral Nervous System"
[1499] "Bone"                      "Bone"                     
[1501] "CNS/Brain"                 "Lung"                     
[1503] "Peripheral Nervous System" "Peripheral Nervous System"
[1505] "Skin"                      "Soft Tissue"              
[1507] "Lung"                      "Kidney"                   
[1509] "Vulva/Vagina"              "Bone"                     
[1511] "Bone"                      "Bone"                     
[1513] "Lung"                      "Skin"                     
[1515] "Skin"                      "Skin"                     
[1517] "Bone"                      "Skin"                     
[1519] "Lung"                      "Lung"                     
[1521] "Bone"                      "Bone"                     
[1523] "Bone"                      "Bone"                     
[1525] "Bone"                      "Bone"                     
[1527] "Bone"                      "Bone"                     
[1529] "Bone"                      "Bone"                     
[1531] "Bone"                      "Bone"                     
[1533] "Bone"                      "Bone"                     
[1535] "Bone"                      "Bone"                     
[1537] "Bone"                      "Vulva/Vagina"             
[1539] "Skin"                      "Lung"                     
[1541] "Pleura"                    "Pleura"                   
[1543] "Pleura"                    "Pleura"                   
[1545] "Pleura"                    "Pleura"                   
[1547] "Pleura"                    "Pleura"                   
[1549] "Pleura"                    "Pleura"                   
[1551] "Pleura"                    "Pleura"                   
[1553] "Pleura"                    "Pleura"                   
[1555] "Lung"                      "Kidney"                   
[1557] "Ovary/Fallopian Tube"      "Esophagus/Stomach"        
[1559] "Bone"                      "Skin"                     
[1561] "Lung"                      "Lung"                     
[1563] "Ovary/Fallopian Tube"      "Skin"                     
[1565] "Thyroid"                   "Ovary/Fallopian Tube"     
[1567] "Kidney"                    "Kidney"                   
[1569] "Skin"                      "Skin"                     
[1571] "Lung"                      "Kidney"                   
[1573] "Lung"                      "Lung"                     
[1575] "Lung"                      "Skin"                     
[1577] "Bone"                      "Esophagus/Stomach"        
[1579] "Skin"                      "Breast"                   
[1581] "Pancreas"                  "Skin"                     
[1583] "Skin"                      "Kidney"                   
[1585] "Kidney"                    "Lung"                     
[1587] "Lung"                      "Lung"                     
[1589] "Lung"                      "Lung"                     
[1591] "Lung"                      "Lung"                     
[1593] "Lung"                      "Bone"                     
[1595] "Breast"                    "Cervix"                   
[1597] "Ovary/Fallopian Tube"      "Ovary/Fallopian Tube"     
[1599] "Ovary/Fallopian Tube"      "Lung"                     
[1601] "Pancreas"                  "Pancreas"                 
[1603] "Kidney"                    "Kidney"                   
[1605] "Kidney"                    "Kidney"                   
[1607] "Kidney"                    "Kidney"                   
[1609] "Lung"                      "Kidney"                   
[1611] "Lung"                      "Lung"                     
[1613] "Other"                     "Kidney"                   
[1615] "Vulva/Vagina"              "Cervix"                   
[1617] "Esophagus/Stomach"         "Bone"                     
[1619] "Skin"                      "Skin"                     
[1621] "Skin"                      "Breast"                   
[1623] "Lymphoid"                  "Myeloid"                  
[1625] "Lymphoid"                  "Head and Neck"            
[1627] "Head and Neck"             "Lymphoid"                 
[1629] "Lymphoid"                  "Lymphoid"                 
[1631] "Peripheral Nervous System" "Myeloid"                  
[1633] "Bowel"                     "Lymphoid"                 
[1635] "Lymphoid"                  "Lymphoid"                 
[1637] "CNS/Brain"                 "CNS/Brain"                
[1639] "CNS/Brain"                 "CNS/Brain"                
[1641] "CNS/Brain"                 "CNS/Brain"                
[1643] "CNS/Brain"                 "CNS/Brain"                
[1645] "CNS/Brain"                 "Lymphoid"                 
[1647] "Bowel"                     "Head and Neck"            
[1649] "Bladder/Urinary Tract"     "Lymphoid"                 
[1651] "Biliary Tract"             "Lymphoid"                 
[1653] "Head and Neck"             "Lymphoid"                 
[1655] "Lymphoid"                  "Lymphoid"                 
[1657] "Esophagus/Stomach"         "Head and Neck"            
[1659] "Lymphoid"                  "Soft Tissue"              
[1661] "Myeloid"                   "Peripheral Nervous System"
[1663] "Head and Neck"             "Head and Neck"            
[1665] "Head and Neck"             "Lymphoid"                 
[1667] "Lymphoid"                  "Lymphoid"                 
[1669] "Lymphoid"                  "Lymphoid"                 
[1671] "CNS/Brain"                 "Myeloid"                  
[1673] "CNS/Brain"                 "Peripheral Nervous System"
[1675] "Myeloid"                   "Esophagus/Stomach"        
[1677] "Esophagus/Stomach"         "Head and Neck"            
[1679] "Bladder/Urinary Tract"     "Lymphoid"                 
[1681] "CNS/Brain"                 "CNS/Brain"                
[1683] "Myeloid"                   "Soft Tissue"              
[1685] "Lymphoid"                  "Myeloid"                  
[1687] "Lymphoid"                  "Lymphoid"                 
[1689] "Myeloid"                   "Peripheral Nervous System"
[1691] "Peripheral Nervous System" "Peripheral Nervous System"
[1693] "Peripheral Nervous System" "Peripheral Nervous System"
[1695] "Peripheral Nervous System" "Peripheral Nervous System"
[1697] "Peripheral Nervous System" "Peripheral Nervous System"
[1699] "Lung"                      "Bowel"                    
[1701] "Testis"                    "Lymphoid"                 
[1703] "Myeloid"                   "Testis"                   
[1705] "Esophagus/Stomach"         "Lymphoid"                 
[1707] "Head and Neck"             "Head and Neck"            
[1709] "Head and Neck"             "Head and Neck"            
[1711] "Head and Neck"             "Myeloid"                  
[1713] "Lymphoid"                  "Lymphoid"                 
[1715] "Myeloid"                   "CNS/Brain"                
[1717] "Head and Neck"             "Esophagus/Stomach"        
[1719] "Lymphoid"                  "Lymphoid"                 
[1721] "Soft Tissue"               "Soft Tissue"              
[1723] "Esophagus/Stomach"         "Biliary Tract"            
[1725] "Lymphoid"                  "Myeloid"                  
[1727] "Myeloid"                   "Lymphoid"                 
[1729] "Breast"                    "Breast"                   
[1731] "Breast"                    "Breast"                   
[1733] "Breast"                    "Breast"                   
[1735] "Breast"                    "Breast"                   
[1737] "Breast"                    "Breast"                   
[1739] "Breast"                    "Breast"                   
[1741] "Breast"                    "Soft Tissue"              
[1743] "Lung"                      "Soft Tissue"              
[1745] "Eye"                       "Lung"                     
[1747] "Skin"                      "Lymphoid"                 
[1749] "Peripheral Nervous System" "Normal"                   
[1751] "Normal"                    "Normal"                   
[1753] "Bowel"                     "Normal"                   
[1755] "Normal"                    "CNS/Brain"                
[1757] "CNS/Brain"                 "Normal"                   
[1759] "Normal"                    "Normal"                   
[1761] "Normal"                    "Normal"                   
[1763] "Normal"                    "Normal"                   
[1765] "Normal"                    "Normal"                   
[1767] "Normal"                    "Normal"                   
[1769] "Normal"                    "Normal"                   
[1771] "Normal"                    "Normal"                   
[1773] "Normal"                    "Normal"                   
[1775] "Normal"                    "Normal"                   
[1777] "Normal"                    "Normal"                   
[1779] "Normal"                    "Normal"                   
[1781] "Normal"                    "Normal"                   
[1783] "Normal"                    "Normal"                   
[1785] "Normal"                    "Normal"                   
[1787] "Normal"                    "Normal"                   
[1789] "Normal"                    "Normal"                   
[1791] "Normal"                    "Skin"                     
[1793] "Skin"                      "Skin"                     
[1795] "Peripheral Nervous System" "Lymphoid"                 
[1797] "Thyroid"                   "Breast"                   
[1799] "Esophagus/Stomach"         "Skin"                     
[1801] "Skin"                      "Skin"                     
[1803] "Skin"                      "Eye"                      
[1805] "Eye"                       "Eye"                      
[1807] "Eye"                       "Eye"                      
[1809] "Eye"                       "Bone"                     
[1811] "Myeloid"                   "Lymphoid"                 
[1813] "Ovary/Fallopian Tube"      "Skin"                     
[1815] "Skin"                      "Skin"                     
[1817] "Skin"                      "Skin"                     
[1819] "Liver"                     "Lung"                     
[1821] "Lung"                      "Biliary Tract"            
[1823] "Lung"                      "Bowel"                    
[1825] "Bowel"                     "Bowel"                    
[1827] "Bowel"                     "Pancreas"                 
[1829] "CNS/Brain"                 "Eye"                      
[1831] "Peripheral Nervous System" "Peripheral Nervous System"
[1833] "Esophagus/Stomach"         "Esophagus/Stomach"        
[1835] "Esophagus/Stomach"         "Pancreas"                 
[1837] "Pancreas"                  "Pancreas"                 
[1839] "Pancreas"                  "Pancreas"                 
[1841] "Esophagus/Stomach"         "Soft Tissue"              
[1843] "Peripheral Nervous System" "Peripheral Nervous System"
[1845] "Bone"                      "Esophagus/Stomach"        
[1847] "Esophagus/Stomach"         "Bowel"                    
[1849] "Skin"                      "Esophagus/Stomach"        
[1851] "Breast"                    "Breast"                   
[1853] "Breast"                    "Peripheral Nervous System"
[1855] "Eye"                       "Breast"                   
[1857] "Breast"                    "Esophagus/Stomach"        
[1859] "Esophagus/Stomach"         "Esophagus/Stomach"        
[1861] "Esophagus/Stomach"         "Esophagus/Stomach"        
[1863] "Esophagus/Stomach"         "Lung"                     

Subsetting a column from a data.frame

metadata$Age[1:5]
[1] 60 36 72 30 30

Challenge!

metadata$Age[metadata$OncotreeLineage == "Myeloid"]
 [1] 36 30 30 64 35 10 77 55 38 35 NA 66 29 63 65  1 64 31 29 71 33 24 58  7 23
[26]  5 47 29 44 73 57 20 77 76 59 35 37 45 40  3 68 46 53 13  0 22  0 62  7 36
[51] 32  0  0 64 64 41 20 63 35 56 37 22 53 33 NA NA  2 28 81 26 52 33 69 51 37
[76]  5 40

Subsetting columns and rows from a data.frame

dataframe[row_idx, col_idx] subsets the data.frame by a row indexing vector row_idx, and a column indexing vector col_idx.

metadata[1:5, c(1, 3)]

Subsetting data.frames

We can refer to the column names directly:

metadata[1:5, c("ModelID", "CellLineName")]

Subsetting columns or rows from a data.frame

We can leave the column index or row index empty to just subset columns or rows.

metadata[1:5, ]

Subsetting Columns or Rows

metadata[, c("ModelID", "CellLineName")]

The crucial bit:

metadata[metadata$OncotreeLineage == "Myeloid",]

Ask me two questions on Slido

https://bit.ly/ir-w2

Week 2 Check-in

https://docs.google.com/forms/d/e/1FAIpQLScByNkcK4xMVosHkIxSXBTrzvSpUqUx01I-_ICvjs3NgZcePg/viewform?usp=sf_link